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Use of Instrumental Variable in Prescription Drug Research with Observational Data: A Systematic Review
OBJECTIVE: Instrumental variable (IV) analysis may offer a useful approach to the problem of unmeasured confounding in prescription drug research if the IV is: 1) strongly and unbiasedly associated to treatment assignment; and 2) uncorrelated with factors predicting the outcome (key assumptions). ST...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079803/ https://ncbi.nlm.nih.gov/pubmed/21163621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2010.09.006 |
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