Genomic instability in induced stem cells

The ability to reprogram adult cells into stem cells has raised hopes for novel therapies for many human diseases. Typical stem cell reprogramming protocols involve expression of a small number of genes in differentiated somatic cells with the c-Myc and Klf4 proto-oncogenes typically included in thi...

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Detalhes bibliográficos
Main Authors: Pasi, C E, Dereli-Öz, A, Negrini, S, Friedli, M, Fragola, G, Lombardo, A, Van Houwe, G, Naldini, L, Casola, S, Testa, G, Trono, D, Pelicci, P G, Halazonetis, T D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079512/
https://ncbi.nlm.nih.gov/pubmed/21311564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.9
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