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The effects of nucleoside analogs on telomerase and telomeres in Tetrahymena.

The ribonucleoprotein enzyme telomerase is a specialized type of cellular reverse transcriptase which synthesizes one strand of telomeric DNA, using as the template a sequence in the RNA moiety of telomerase. We analyzed the effects of various nucleoside analogs, known to be chain-terminating inhibi...

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Detalles Bibliográficos
Main Authors: Strahl, C, Blackburn, E H
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC307907/
https://ncbi.nlm.nih.gov/pubmed/8152919
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