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Persistent anxiolytic affects after chronic administration of the CRF(1) receptor antagonist R121919 in rats
Corticotropin-releasing factor (CRF) functions as one of the major mediators of the mammalian stress response and appears to play a key role in the pathophysiology of mood and anxiety disorders. Small molecule CRF(1) receptor antagonists may represent a novel form of pharmacotherapy for these disord...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079005/ https://ncbi.nlm.nih.gov/pubmed/20951149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.10.004 |
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