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Persistent anxiolytic affects after chronic administration of the CRF(1) receptor antagonist R121919 in rats

Corticotropin-releasing factor (CRF) functions as one of the major mediators of the mammalian stress response and appears to play a key role in the pathophysiology of mood and anxiety disorders. Small molecule CRF(1) receptor antagonists may represent a novel form of pharmacotherapy for these disord...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gutman, David A., Owens, Michael J., Thrivikraman, K.V., Nemeroff, Charles B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079005/
https://ncbi.nlm.nih.gov/pubmed/20951149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.10.004
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