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Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood–brain barrier disruption
Previous studies have shown that plasmin cleaves monocyte chemoattractant protein 1 (MCP1; officially known as C-C motif chemokine 2, CCL2) at K104, and this cleavage enhances its chemotactic potency significantly. Accumulating evidence reveals that MCP1 also disrupts the integrity of the blood–brai...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078815/ https://ncbi.nlm.nih.gov/pubmed/21486949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.082834 |
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