Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity

AIMS: It has been well demonstrated that phosphodiesterase-5A (PDE5A) is expressed in smooth muscle cells and plays an important role in regulation of vascular tone. The role of endothelial PDE5A, however, has not been yet characterized. The present study was undertaken to determine the presence, lo...

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主要な著者: Gebska, Milena A., Stevenson, Blake K., Hemnes, Anna R., Bivalacqua, Trinity J., Haile, Azeb, Hesketh, Geoffrey G., Murray, Christopher I., Zaiman, Ari L., Halushka, Marc K., Krongkaew, Nispa, Strong, Travis D., Cooke, Carol A., El-Haddad, Hazim, Tuder, Rubin M., Berkowitz, Dan E., Champion, Hunter C.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078797/
https://ncbi.nlm.nih.gov/pubmed/21421555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq410
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