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A conserved mechanism of DEAD-box ATPase activation by nucleoporins and IP(6) in mRNA export
Superfamily 1 (SF1) and superfamily 2 (SF2) RNA helicases are ubiquitous mRNA-protein (mRNP) remodelling enzymes that play critical roles in all aspects of RNA metabolism1, 2. The SF2 DEAD-box ATPase Dbp5/Ddx19 functions in mRNA export and is thought to remodel mRNPs at the nuclear pore complex (NPC...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078754/ https://ncbi.nlm.nih.gov/pubmed/21441902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09862 |
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