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Ocular Sustained Release Nanoparticles Containing Stereoisomeric Dipeptide Prodrugs of Acyclovir

PURPOSE: The objective of this study was to develop and characterize polymeric nanoparticles of appropriate stereoisomeric dipeptide prodrugs of acyclovir (L-valine-L-valine-ACV, L-valine-D-valine-ACV, D-valine-L-valine-ACV, and D-valine-D-valine-ACV) for the treatment of ocular herpes keratitis. ME...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jwala, Jwala, Boddu, Sai H.S., Shah, Sujay, Sirimulla, Suman, Pal, Dhananjay, Mitra, Ashim K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078652/
https://ncbi.nlm.nih.gov/pubmed/21500985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2010.0188
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