Structure of Mammalian AMPK and its regulation by ADP

The heterotrimeric AMP-activated protein kinase (AMPK) plays a key role in regulating cellular energy metabolism; in response to a fall in intracellular ATP levels it activates energy producing pathways and inhibits energy consuming processes1. AMPK has been implicated in a number of diseases relate...

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Autori principali: Xiao, Bing, Sanders, Matthew J., Underwood, Elizabeth, Heath, Richard, Mayer, Faith, Carmena, David, Jing, Chun, Walker, Philip A., Eccleston, John F., Haire, Lesley F., Saiu, Peter, Howell, Steven A., Aasland, Rein, Martin, Stephen R., Carling, David, Gamblin, Steven J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078618/
https://ncbi.nlm.nih.gov/pubmed/21399626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09932
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