Detection of HER2 amplification in circulating free DNA in patients with breast cancer

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in 20–25% of breast cancers. This study investigated circulating free DNA (cfDNA) for detection of HER2 gene amplification in patients with breast cancer. METHODS: Circulating free DNA was extracted from plasm...

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Detalhes bibliográficos
Main Authors: Page, K, Hava, N, Ward, B, Brown, J, Guttery, D S, Ruangpratheep, C, Blighe, K, Sharma, A, Walker, R A, Coombes, R C, Shaw, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078598/
https://ncbi.nlm.nih.gov/pubmed/21427727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.89
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