Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer

BACKGROUND: Circulating tumour cells (CTCs) offer a non-invasive approach to obtain and characterise metastatic tumour cells, but their usefulness has been limited by low CTC yields from conventional isolation methods. METHODS: To improve CTC yields and facilitate their molecular characterisation we...

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Detalhes bibliográficos
Main Authors: Flores, L M, Kindelberger, D W, Ligon, A H, Capelletti, M, Fiorentino, M, Loda, M, Cibas, E S, Jänne, P A, Krop, I E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869174/
https://ncbi.nlm.nih.gov/pubmed/20461092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605676
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