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Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.

Tissue-specific expression of the human adenosine deaminase (ADA) gene is mediated by transcriptional activation over a thousand-fold range. Cis-regulatory regions responsible for high and basal levels of activation include an enhancer and the proximal promoter region. While analyses of the T-cell s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dusing, M R, Wiginton, D A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC307859/
https://ncbi.nlm.nih.gov/pubmed/8127716
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