Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.
Tissue-specific expression of the human adenosine deaminase (ADA) gene is mediated by transcriptional activation over a thousand-fold range. Cis-regulatory regions responsible for high and basal levels of activation include an enhancer and the proximal promoter region. While analyses of the T-cell s...
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| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1994
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307859/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.4.669 |
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