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Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.

Tissue-specific expression of the human adenosine deaminase (ADA) gene is mediated by transcriptional activation over a thousand-fold range. Cis-regulatory regions responsible for high and basal levels of activation include an enhancer and the proximal promoter region. While analyses of the T-cell s...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Dusing, M R, Wiginton, D A
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 1994
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.4.669
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