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Alteration in the Gene Encoding Protein Tyrosine Phosphatase Nonreceptor Type 6 (PTPN6/SHP1) May Contribute to Neutrophilic Dermatoses

We have found a B2 repeat insertion in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6) in a mouse that developed a skin disorder with clinical and histopathological features resembling those seen in human neutrophilic dermatoses. Neutrophilic dermatoses are a group of compl...

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Bibliografske podrobnosti
Main Authors: Nesterovitch, Andrew B., Gyorfy, Zsuzsa, Hoffman, Mark D., Moore, Ellen C., Elbuluk, Nada, Tryniszewska, Beata, Rauch, Tibor A., Simon, Melinda, Kang, Sewon, Fisher, Gary J., Mikecz, Katalin, Tharp, Michael D., Glant, Tibor T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078441/
https://ncbi.nlm.nih.gov/pubmed/21406173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.035
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