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Alteration in the Gene Encoding Protein Tyrosine Phosphatase Nonreceptor Type 6 (PTPN6/SHP1) May Contribute to Neutrophilic Dermatoses

We have found a B2 repeat insertion in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6) in a mouse that developed a skin disorder with clinical and histopathological features resembling those seen in human neutrophilic dermatoses. Neutrophilic dermatoses are a group of compl...

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Détails bibliographiques
Auteurs principaux: Nesterovitch, Andrew B., Gyorfy, Zsuzsa, Hoffman, Mark D., Moore, Ellen C., Elbuluk, Nada, Tryniszewska, Beata, Rauch, Tibor A., Simon, Melinda, Kang, Sewon, Fisher, Gary J., Mikecz, Katalin, Tharp, Michael D., Glant, Tibor T.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078441/
https://ncbi.nlm.nih.gov/pubmed/21406173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.035
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