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Rescue of Calcineurin Aα(−/−) Mice Reveals a Novel Role for the α Isoform in the Salivary Gland
Calcineurin is an important signal transduction mediator in T cells, neurons, the heart, and kidneys. Recent evidence points to unique actions of the two main isoforms of the catalytic subunit. Although the β isoform is required for T-cell development, α is important in the brain and kidney. In addi...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Investigative Pathology
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078436/ https://ncbi.nlm.nih.gov/pubmed/21435446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.054 |
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