Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

Neural stem cells (NSCs) generate new granule cells throughout life in the mammalian hippocampus. Canonical Wnt signaling regulates the differentiation of NSCs towards the neuronal lineage. Here we identified the prospero-related homeodomain transcription factor Prox1 as a target of β-catenin–TCF/LE...

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Bibliografske podrobnosti
Main Authors: Karalay, Özlem, Doberauer, Kathrin, Vadodaria, Krishna C., Knobloch, Marlen, Berti, Lucia, Miquelajauregui, Amaya, Schwark, Manuela, Jagasia, Ravi, Taketo, Makoto M., Tarabykin, Victor, Lie, D. Chichung, Jessberger, Sebastian
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078392/
https://ncbi.nlm.nih.gov/pubmed/21436036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013456108
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