Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

Neural stem cells (NSCs) generate new granule cells throughout life in the mammalian hippocampus. Canonical Wnt signaling regulates the differentiation of NSCs towards the neuronal lineage. Here we identified the prospero-related homeodomain transcription factor Prox1 as a target of β-catenin–TCF/LE...

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Detalhes bibliográficos
Main Authors: Karalay, Özlem, Doberauer, Kathrin, Vadodaria, Krishna C., Knobloch, Marlen, Berti, Lucia, Miquelajauregui, Amaya, Schwark, Manuela, Jagasia, Ravi, Taketo, Makoto M., Tarabykin, Victor, Lie, D. Chichung, Jessberger, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078392/
https://ncbi.nlm.nih.gov/pubmed/21436036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013456108
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