Rosmarinic Acid, Active Component of Dansam-Eum Attenuates Ototoxicity of Cochlear Hair Cells through Blockage of Caspase-1 Activity

Cisplatin causes auditory impairment due to the apoptosis of auditory hair cells. There is no strategy to regulate ototoxicity by cisplatin thus far. Dansam-Eum (DSE) has been used for treating the central nerve system injury including hearing loss in Korea. However, disease-related scientific inves...

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Detalhes bibliográficos
Main Authors: Jeong, Hyun-Ja, Choi, Youngjin, Kim, Min-Ho, Kang, In-Cheol, Lee, Jeong-Han, Park, Channy, Park, Raekil, Kim, Hyung-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078149/
https://ncbi.nlm.nih.gov/pubmed/21526214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018815
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