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Antigen-Specific Monoclonal Antibodies Isolated from B Cells Expressing Constitutively Active STAT5
BACKGROUND: Fully human monoclonal antibodies directed against specific pathogens have a high therapeutic potential, but are difficult to generate. METHODOLOGY/PRINCIPAL FINDINGS: Memory B cells were immortalized by expressing an inducible active mutant of the transcription factor Signal Transducer...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078118/ https://ncbi.nlm.nih.gov/pubmed/21525985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017189 |
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