Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates

BACKGROUND: Rodent studies show that neurogenesis is necessary for mediating the salutary effects of antidepressants. Nonhuman primate (NHP) studies may bridge important rodent findings to the clinical realm since NHP-depression shares significant homology with human depression and kinetics of prima...

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Главные авторы: Perera, Tarique D., Dwork, Andrew J., Keegan, Kathryn A., Thirumangalakudi, Lakshmi, Lipira, Cecilia M., Joyce, Niamh, Lange, Christopher, Higley, J. Dee, Rosoklija, Gorazd, Hen, Rene, Sackeim, Harold A., Coplan, Jeremy D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078107/
https://ncbi.nlm.nih.gov/pubmed/21525974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017600
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