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Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates

BACKGROUND: Rodent studies show that neurogenesis is necessary for mediating the salutary effects of antidepressants. Nonhuman primate (NHP) studies may bridge important rodent findings to the clinical realm since NHP-depression shares significant homology with human depression and kinetics of prima...

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Detalhes bibliográficos
Main Authors: Perera, Tarique D., Dwork, Andrew J., Keegan, Kathryn A., Thirumangalakudi, Lakshmi, Lipira, Cecilia M., Joyce, Niamh, Lange, Christopher, Higley, J. Dee, Rosoklija, Gorazd, Hen, Rene, Sackeim, Harold A., Coplan, Jeremy D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078107/
https://ncbi.nlm.nih.gov/pubmed/21525974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017600
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