Antiviral propierties of 5,5'-dithiobis-2-nitrobenzoic acid and bacitracin against T-tropic human immunodeficiency virus type 1

Bacitracin and the membrane-impermeant thiol reagent 5,5'-dithiobis-2-nitrobenzoic acid (DTNB) are agents known to inhibit protein disulfide isomerase (PDI), a cell-surface protein critical in HIV-1 entry therefore they are fusion inhibitors (FI). Here we investigated the possibility that Bacit...

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Autori principali: Lara, Humberto H, Ixtepan-Turrent, Liliana, Garza-Treviño, Elsa N, Flores-Teviño, Samantha M, Borkow, Gadi, Rodriguez-Padilla, Cristina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078101/
https://ncbi.nlm.nih.gov/pubmed/21435237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-137
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