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Vacuolization of mucolipidosis type II mouse exocrine gland cells represents accumulation of autolysosomes
We previously reported that mice deficient in UDP-GlcNAc:lysosomal enzyme GlcNAc-1-phosphotransferase (mucolipidosis type II or Gnptab −/− mice), the enzyme that initiates the addition of the mannose 6-phosphate lysosomal sorting signal on acid hydrolases, exhibited extensive vacuolization of their...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078071/ https://ncbi.nlm.nih.gov/pubmed/21325625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-07-0584 |
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