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Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin

In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset...

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Bibliografiske detaljer
Main Authors: Bossert, Jennifer M., Stern, Anna L., Theberge, Florence R.M., Cifani, Carlo, Koya, Eisuke, Hope, Bruce T., Shaham, Yavin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077927/
https://ncbi.nlm.nih.gov/pubmed/21336273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2758
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