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Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin
In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077927/ https://ncbi.nlm.nih.gov/pubmed/21336273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2758 |
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