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Conversion of scFv peptide-binding specificity for crystal chaperone development

In spite of advances in protein expression and purification over the last decade, many proteins remain recalcitrant to structure determination by X-ray crystallography. One emerging tactic to obtain high-quality protein crystals for structure determination, particularly in the case of membrane prote...

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Detalles Bibliográficos
Main Authors: Pai, Jennifer C., Culver, Jeffrey A., Drury, Jason E., Motani, Rakesh S., Lieberman, Raquel L., Maynard, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077810/
https://ncbi.nlm.nih.gov/pubmed/21217145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq120
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