Oxidative DNA Damage Bypass in Arabidopsis thaliana Requires DNA Polymerase λ and Proliferating Cell Nuclear Antigen 2([W])

The oxidized base 7,8-oxoguanine (8-oxo-G) is the most common DNA lesion generated by reactive oxygen species. This lesion is highly mutagenic due to the frequent misincorporation of A opposite 8-oxo-G during DNA replication. In mammalian cells, the DNA polymerase (pol) family X enzyme DNA pol λ cat...

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Detalhes bibliográficos
Main Authors: Amoroso, Alessandra, Concia, Lorenzo, Maggio, Caterina, Raynaud, Cécile, Bergounioux, Catherine, Crespan, Emmanuele, Cella, Rino, Maga, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Biologists 2011
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077771/
https://ncbi.nlm.nih.gov/pubmed/21325140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.110.081455
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