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A New State of Cardiac Myosin with Very Slow ATP Turnover: A Potential Cardioprotective Mechanism in the Heart

The mechanisms that control cardiac contractility are complex. Recent work we conducted in vertebrate skeletal muscle identified a new state of myosin, the super-relaxed state (SRX), which had a very low metabolic rate. To determine whether this state also exists in cardiac muscle we used quantitati...

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Detalhes bibliográficos
Main Authors: Hooijman, Pleuni, Stewart, Melanie A., Cooke, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077696/
https://ncbi.nlm.nih.gov/pubmed/21504733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.02.061
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