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Missing-base and ethylation interference footprinting of P1 plasmid replication initiator.
RepA, the replication initiator protein of plasmid P1, binds to specific 19 bp sequences on the plasmid DNA. Earlier footprinting studies with dimethylsulfate identified the guanines that contact RepA through the major groove of DNA. In this study, base elimination was used to identify the contribut...
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| Главные авторы: | , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1994
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307765/ https://ncbi.nlm.nih.gov/pubmed/8121798 |
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