An Early Response Transcription Factor, Egr-1, Enhances Insulin Resistance in Type 2 Diabetes with Chronic Hyperinsulinism

One of the most important characteristics of type 2 diabetes is insulin resistance, during which the patients normally experienced hyperinsulinism stress that would alter insulin signal transduction in insulin target tissues. We have previously found that early growth responsive gene-1 (Egr-1), a zi...

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Bibliographic Details
Main Authors: Shen, Ning, Yu, Xiao, Pan, Fei-Yan, Gao, Xiang, Xue, Bin, Li, Chao-Jun
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077649/
https://ncbi.nlm.nih.gov/pubmed/21321112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190165
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