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Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death

Evidence suggests that the C-terminal truncation of α-synuclein is equally important as aggregation of α-synuclein in Parkinson disease (PD). Our previous results showed that an endopeptidase, matrix metalloproteinase-3 (MMP3), was induced and activated in dopaminergic (DA) cells upon stress conditi...

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Hlavní autoři: Choi, Dong-Hee, Kim, Youn-Jung, Kim, Young-Gun, Joh, Tong H., Beal, M. Flint, Kim, Yoon-Seong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077618/
https://ncbi.nlm.nih.gov/pubmed/21330369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222430
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