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A direct selection strategy for shotgun cloning and sequencing in the bacteriophage M13.

A new cloning strategy is described which utilizes direct selection of recombinants for shotgun sequencing in the filamentous bacteriophage M13. Direct selection is accomplished by insertional inactivation of the M13 gene X protein, a powerful inhibitor of phage-specific DNA synthesis when overprodu...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Guilfoyle, R A, Smith, L M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1994
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8127645/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.1.100
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