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Gene Expression Profiling in a Mouse Model Identifies Fetal Liver- and Placenta-Derived Potential Biomarkers for Down Syndrome Screening

BACKGROUND: As a first step to identify novel potential biomarkers for prenatal Down Syndrome screening, we analyzed gene expression in embryos of wild type mice and the Down Syndrome model Ts1Cje. Since current Down Syndrome screening markers are derived from placenta and fetal liver, these tissues...

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Bibliografische gegevens
Hoofdauteurs: Pennings, Jeroen L. A., Rodenburg, Wendy, Imholz, Sandra, Koster, Maria P. H., van Oostrom, Conny T. M., Breit, Timo M., Schielen, Peter C. J. I., de Vries, Annemieke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077415/
https://ncbi.nlm.nih.gov/pubmed/21533146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018866
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