Gene Expression Profiling in a Mouse Model Identifies Fetal Liver- and Placenta-Derived Potential Biomarkers for Down Syndrome Screening

BACKGROUND: As a first step to identify novel potential biomarkers for prenatal Down Syndrome screening, we analyzed gene expression in embryos of wild type mice and the Down Syndrome model Ts1Cje. Since current Down Syndrome screening markers are derived from placenta and fetal liver, these tissues...

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Detalhes bibliográficos
Main Authors: Pennings, Jeroen L. A., Rodenburg, Wendy, Imholz, Sandra, Koster, Maria P. H., van Oostrom, Conny T. M., Breit, Timo M., Schielen, Peter C. J. I., de Vries, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077415/
https://ncbi.nlm.nih.gov/pubmed/21533146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018866
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