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Delineation of Stage Specific Expression of Plasmodium falciparum EBA-175 by Biologically Functional Region II Monoclonal Antibodies

BACKGROUND: The malaria parasite Plasmodium falciparum EBA-175 binds its receptor sialic acids on glycophorin A when invading erythrocytes. The receptor-binding region (RII) contains two cysteine-rich domains with similar cysteine motifs (F1 and F2). Functional relationships between F1 and F2 domain...

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Detalhes bibliográficos
Main Authors: Sim, B. Kim Lee, Narum, David L., Chattopadhyay, Rana, Ahumada, Adriana, Haynes, J. David, Fuhrmann, Steven R., Wingard, Jennifer N., Liang, Hong, Moch, J. Kathleen, Hoffman, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077373/
https://ncbi.nlm.nih.gov/pubmed/21533224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018393
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