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A New Model to Produce Infectious Hepatitis C Virus without the Replication Requirement
Numerous constraints significantly hamper the experimental study of hepatitis C virus (HCV). Robust replication in cell culture occurs with only a few strains, and is invariably accompanied by adaptive mutations that impair in vivo infectivity/replication. This problem complicates the production and...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077361/ https://ncbi.nlm.nih.gov/pubmed/21533214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001333 |
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