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Role of the Asialoglycoprotein Receptor in Binding and Entry of Hepatitis C Virus Structural Proteins in Cultured Human Hepatocytes

We used a baculovirus-based system to prepare structural proteins of hepatitis C virus (HCV) genotype 1a. Binding of this preparation to cultured human hepatic cells was both dose dependent and saturable. This binding was decreased by calcium depletion and was partially prevented by ligands of the a...

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Detalhes bibliográficos
Main Authors: Saunier, Bertrand, Triyatni, Miriam, Ulianich, Luca, Maruvada, Padma, Yen, Paul, Kohn, Leonard D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC140572/
https://ncbi.nlm.nih.gov/pubmed/12477859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.546-559.2003
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