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Role of the Asialoglycoprotein Receptor in Binding and Entry of Hepatitis C Virus Structural Proteins in Cultured Human Hepatocytes

We used a baculovirus-based system to prepare structural proteins of hepatitis C virus (HCV) genotype 1a. Binding of this preparation to cultured human hepatic cells was both dose dependent and saturable. This binding was decreased by calcium depletion and was partially prevented by ligands of the a...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Saunier, Bertrand, Triyatni, Miriam, Ulianich, Luca, Maruvada, Padma, Yen, Paul, Kohn, Leonard D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140572/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12477859/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.1.546-559.2003
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