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Selective Deletion of a Cell Cycle Checkpoint Kinase (ATR) Reduces Neurogenesis and Alters Responses in Rodent Models of Behavioral Affect

Hippocampal function has been implicated in mood and anxiety disorders, as well as in the response to antidepressant (AD) treatment. However, the significance of new neurons in the therapeutic mechanism of ADs remains unclear. In this study, the proliferation of new neurons was inhibited through con...

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Autors principals: Onksen, Jennifer L, Brown, Eric J, Blendy, Julie A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077265/
https://ncbi.nlm.nih.gov/pubmed/21248719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.234
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