Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implications

Colorectal cancer (CRC) is a complex disease related to environmental and genetic risk factors. Several studies have shown that susceptibility to complex diseases can be mediated by ancestral alleles. Using RNAi screening, CTNNBL1 was identified as a putative regulator of the Wnt signaling pathway,...

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Hlavní autoři: Huhn, Stefanie, Ingelfinger, Dierk, Bermejo, Justo Lorenzo, Bevier, Melanie, Pardini, Barbara, Naccarati, Alessio, Steinke, Verena, Rahner, Nils, Holinski-Feder, Elke, Morak, Monika, Schackert, Hans K, Görgens, Heike, Pox, Christian P, Goecke, Timm, Kloor, Matthias, Loeffler, Markus, Büttner, Reinhard, Vodickova, Ludmila, Novotny, Jan, Demir, Kubilay, Cruciat, Cristina-Maria, Renneberg, Rebecca, Huber, Wolfgang, Niehrs, Christof, Boutros, Michael, Propping, Peter, Vodička, Pavel, Hemminki, Kari, Försti, Asta
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077237/
https://ncbi.nlm.nih.gov/pubmed/21537400
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