Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implications

Colorectal cancer (CRC) is a complex disease related to environmental and genetic risk factors. Several studies have shown that susceptibility to complex diseases can be mediated by ancestral alleles. Using RNAi screening, CTNNBL1 was identified as a putative regulator of the Wnt signaling pathway,...

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Detalhes bibliográficos
Main Authors: Huhn, Stefanie, Ingelfinger, Dierk, Bermejo, Justo Lorenzo, Bevier, Melanie, Pardini, Barbara, Naccarati, Alessio, Steinke, Verena, Rahner, Nils, Holinski-Feder, Elke, Morak, Monika, Schackert, Hans K, Görgens, Heike, Pox, Christian P, Goecke, Timm, Kloor, Matthias, Loeffler, Markus, Büttner, Reinhard, Vodickova, Ludmila, Novotny, Jan, Demir, Kubilay, Cruciat, Cristina-Maria, Renneberg, Rebecca, Huber, Wolfgang, Niehrs, Christof, Boutros, Michael, Propping, Peter, Vodička, Pavel, Hemminki, Kari, Försti, Asta
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077237/
https://ncbi.nlm.nih.gov/pubmed/21537400
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