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Molecular determinants of Ca(2+)/calmodulin-dependent regulation of Ca(v)2.1 channels
Ca(2+)-dependent facilitation and inactivation (CDF and CDI) of Ca(v)2.1 channels modulate presynaptic P/Q-type Ca(2+) currents and contribute to activity-dependent synaptic plasticity. This dual feedback regulation by Ca(2+) involves calmodulin (CaM) binding to the α(1) subunit (α(1)2.1). The molec...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673106/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2237000100 |
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