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Random Treatment Assignment Using Mathematical Equipoise for Comparative Effectiveness Trials

In controlled clinical trials, random assignment of treatment is appropriate only when there is equipoise, that is, no clear preference among treatment options. However, even when equipoise appears absent because prior trials show, on average, one treatment yields superior outcomes, random assignmen...

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Autors principals: Selker, Harry P., Ruthazer, Robin, Terrin, Norma, Griffith, John L., Concannon, Thomas, Kent, David M.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076795/
https://ncbi.nlm.nih.gov/pubmed/21348950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2010.00253.x
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