Departures from community equipoise may lead to incorrect inference in randomized trials

OBJECTIVE: To assess the impact of selective enrollment on the results of randomized, controlled trials (RCTs). STUDY DESIGN AND SETTING: We simulated a RCT of arthroscopic partial meniscectomy vs. nonoperative therapy in patients with meniscal tear and osteoarthritis (OA). We estimated efficacy wit...

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Huvudupphovsmän: Katz, Jeffrey N., Wright, John, Levy, Bruce A., Baron, John A., Losina, Elena
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958234/
https://ncbi.nlm.nih.gov/pubmed/20638236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jclinepi.2010.04.008
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