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Functionally Important Positions Can Comprise the Majority of a Protein's Architecture

Concomitant with the genomic era, many bioinformatics programs have been developed to identify functionally important positions from sequence alignments of protein families. To evaluate these analyses, many have used the LacI/GalR family and determined whether positions predicted to be “important” a...

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Bibliographic Details
Main Authors: Tungtur, Sudheer, Parente, Daniel J., Swint-Kruse, Liskin
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076786/
https://ncbi.nlm.nih.gov/pubmed/21374721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22985
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