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Functional Consequences of Exchanging Domains Between LacI and PurR are Mediated by the Intervening Linker Sequence

Homologue function can be differentiated by changing residues that affect binding sites or long-range interactions. LacI and PurR are two proteins that represent the LacI/GalR family (>500 members) of bacterial transcription regulators. All members have distinct DNA-binding and regulatory domains...

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Autori principali: Tungtur, Sudheer, Egan, Susan M., Swint-Kruse, Liskin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084478/
https://ncbi.nlm.nih.gov/pubmed/17436321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21412
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