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Examining the Statistical Properties of Fine-Scale Mapping in Large-Scale Association Studies

Interpretation of dense single nucleotide polymorphism (SNP) follow-up of genome-wide association or linkage scan signals can be facilitated by establishing expectation for the behaviour of primary mapping signals upon fine-mapping, under both null and alternative hypotheses. We examined the inferen...

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Bibliographic Details
Main Authors: Wiltshire, Steven, Morris, Andrew P., Zeggini, Eleftheria
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076696/
https://ncbi.nlm.nih.gov/pubmed/18064636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20295
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