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New insights into the GABA(A) receptor structure and orthosteric ligand binding: Receptor modeling guided by experimental data
GABA(A) receptors (GABA(A)Rs) are ligand gated chloride ion channels that mediate overall inhibitory signaling in the CNS. A detailed understanding of their structure is important to gain insights in e.g. ligand binding and functional properties of this pharmaceutically important target. Homology mo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076690/ https://ncbi.nlm.nih.gov/pubmed/21365676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22975 |
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