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Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon
An estimated one-third of the world's population is latently infected with Mycobacterium tuberculosis, the etiologic agent of tuberculosis. Here, we demonstrate that, unlike wild-type M. tuberculosis, a strain of M. tuberculosis disrupted in the mce1 operon was unable to enter a stable persiste...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307668/ https://ncbi.nlm.nih.gov/pubmed/14663145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2433882100 |
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